George Washington sends Daniel and Yadkin into ""Ken-Tuck-E,"" the ""dark and bloody"" hunting ground of four Indian nations, to find a site for a fort. Once they arrive, they encounter representatives of two of those four nations -- Shawnee warriors chasing a lone Cherokee warrior. Daniel helps drive the Shawnee away, and the grateful Cherokee, Mingo, returns the favor by showing Daniel and Yad an ideal location to build their fort. Yad returns east while Daniel remains with Mingo to explore the country.

Boone invites a widow (Bethel Leslie) and her hungry brood to town, but one of the children steals a telescope.

British soldiers and Indians surround Jemima as she tries to help Boone, wounded in the wilderness.

Boone chases a river pirate (Emile Genest) who plans to sell a load of stolen arms to Shawnees.

A British officer (Michael Rennie) captures Boone then impersonates him to win Indian allies; guest Frank DeKova

Israel becomes lost in the woods after fur thieves ambush him, Boone and Yadkin.

Yadkin's trickery leaves Boone the unexpected, and unwilling, owner of indentured Irish sisters (Fay Spain, Nina Shipman).

A bondsman (Peter Whitney) insists on returning a runaway slave (Brock Peters) unshackled by Boone.

Mingo plans to do more than protest a new treaty when he and Boone visit Virginia's governor general (Walter Pidgeon)

Boone cannot believe a boyhood friend (Pat Hingle) murdered two Cherokee youths.

A Shawnee prophet (John Russell) predicts massacre for the settlers of Boonesborough; guest Patricia Huston.

Boone befriends a mother (Geraldine Brooks) and son (Kurt Russell), but learns the woman is accused of witchcraft.

While hunting, the Boones meet a delirious British officer (Macdonald Carey) pursued by vengeful Shawnees.

A condemned bounty hunter (Dan Duryea) who escaped from a military convoy takes the Boones hostage.

Boone assists a boy (Kurt Russell) and winds up at the mercy of a larcenous clan; guests Lloyd Nolan, Lane Bradford.

A Quaker family refuses to fight until Indians kidnap a daughter; guests Alexander Scourby, Jay Silverheels.

Boone commands four criminals recruited by Yadkin to haul frieght to Boonesborough; guests Sean McClory, Gordon Jump.

An idealistic schoolteacher (George Gobel) incites Boonesborough's wrath by giving gunpowder to the Shawnees.

Boone seems guilty of betrayal when he allows Choctaws to capture the town's men

Lacking water and powder, the women and children of Boonesborough seem easy prey for attacking Choctaws.